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Organic compounds in which a hydrogen atom or more has been replaced by a halogen atom in an alkane molecule (saturated hydrocarbon chain). Halogen atoms include bromine, chlorine, fluorine, and iodine. Compounds may be in closed ring configurations.
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Bis(2-bromoethyl) ether is an alkyl chain-based PROTAC linker utilized in the synthesis of PROTACs (Proteolysis Targeting Chimeras). PROTACs are designed to degrade target proteins by exploiting the intracellular ubiquitin-proteasome system.
Alkyl chain-based PROTAC linker used in the synthesis of PROTACs.
Facilitates targeted protein degradation via the ubiquitin-proteasome system.
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MK-4101 is a small-molecule Smoothened (SMO) antagonist that inhibits the Hedgehog signaling pathway and is used for in vitro cancer and signaling research. Supplied as a ready-to-use 10 mM solution in DMSO (1 mL), the compound is characterized by a confirmed CAS number and molecular weight and should be stored frozen and aliquoted to preserve activity.
Potent SMO antagonist suitable for Hedgehog pathway studies.
Ready-to-use 10 mM solution in DMSO for rapid experiment setup.
Small 1 mL format ideal for pilot studies and limited-scope assays.
Well-characterized identity with CAS 935273-79-3 and confirmed molecular weight.
Store at -20 °C and aliquot to avoid multiple freeze-thaw cycles.
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WM-1119 is a small-molecule inhibitor of lysine acetyltransferase 6A (KAT6A/MOZ) used as a biochemical probe in epigenetics and oncology research. It exhibits potent biochemical activity (KAT6A IC50 = 6.3 nM) and demonstrated cellular activity (EMRK1184 B-cell lymphoma IC50 = 0.25 μM). Key identifiers: CAS 2055397-28-7; formula C18H13F2N3O3S; molecular weight 389.4 g/mol; purity ≥98%.
Potent KAT6A inhibition (IC50 = 6.3 nM).
Demonstrated cellular activity in lymphoma cells (IC50 = 0.25 μM).
High purity supports reproducible biochemical assays (≥98%).
Well-defined molecular properties for characterization.
Suitable as a research chemical probe in epigenetic studies.
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(1-Bromoethyl)benzene-d3 is the deuterium-labeled isotopologue of (1-Bromoethyl)benzene intended for research and analytical applications. It is supplied in small milligram quantities and is accompanied by documentation for safe handling and quality verification.
Deuterium-labeled isotopologue for use as a stable isotope standard or tracer.
Purity 98.7%.
Molecular formula C8H6D3, molecular weight 188.08.
Appearance: liquid, light yellow to light brown.
Available in small milligram packages for analytical workflows.
Data sheet, safety data sheet, and certificate of analysis available for download.
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